Antioxidant properties of amide derivatives of 3,4-dihydropyrimidin-2-one with phenolic substituent in heterocycle
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چکیده
منابع مشابه
Antioxidant properties of phenolic compounds
The addition of synthetic antioxidants to oils and/or foods is one of the most efficient ways to prevent lipid oxidation. However, the safety of synthetic additives has been questioned stimulating the evaluation of naturally occurring compounds with antioxidative properties. Although there is no assurance of the safety of natural antioxidants, there is some comfort knowing that such antioxidant...
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Novel alkynyl substituted 3,4-dihydropyrimidin-2(1H)-one derivatives as potential inhibitors of chorismate mutase.
A series of novel alkynyl substituted 3,4-dihydropyrimidin-2(1H)-one (DHPM) derivatives were designed, synthesized and evaluated in vitro as potential inhibitors of chorismate mutase (CM). All these compounds were prepared via a multi-component reaction (MCR) involving sequential I2-mediated Biginelli reaction followed by Cu-free Sonogashira coupling. Some of them showed promising inhibitory ac...
متن کاملOxalic acid dihydrate catalyzed synthesis of 3,4-dihydropyrimidin-2-(1H)-one derivatives under thermal and solvent-free conditions
Oxalic acid dihydrate as a green, mild and efficient catalyst for the one-pot three-component Biginelli synthesis of 3,4-dihydropyrimidin-2-(1H)-one derivatives from the reaction between β-keto esters (methyl or ethyl acetoacetate), aromatic aldehyde (benzaldehye derivatives) and urea or thiourea under thermal and solvent-free conditions with excellent yields and short reaction time is st...
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ژورنال
عنوان ژورنال: Chernivtsi University Scientific Herald. Chemistry
سال: 2019
ISSN: 2710-2483,2223-1722
DOI: 10.31861/chem-2019-819-08